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A 27 year old female presents to ED with a fever and headache. She has just returned from Kenya after a 2 week holiday.

Her vital signs are:

  • HR 110 bpm
  • Sats 96 % on air
  • BP 100/60 mmHg
  • Temp 38.6 Β°C

1. List (4) differential diagnoses and for each diagnosis please list (2) supporting features on history or examination 12 marks

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A VBG and FBE are performed and shown below :

  • pH 7.28
  • CO2 30
  • HCO3 18
  • Lactate 4.0
  • BSL 10
  • pO2 50
  • Hb 70
  • MCV 80
  • Plt 150
  • WCC 18.5

2. What is the most likely diagnosis? 1 mark

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3. State your (5) immediate steps in the management of this patient. 5 marks

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