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A 62-year-old woman with end-stage kidney disease managed with long-term continuous ambulatory peritoneal dialysis (CAPD) presents to the Emergency Department with 24 hours of worsening abdominal pain and nausea. She is seen by a junior doctor who reports that her peritoneal dialysis effluent has appeared cloudy since this morning.

She is otherwise independent and usually manages her dialysis at home.

Her vitals on presentation are:

  • BP 110/68 mmHg
  • HR 102 bpm
  • RR 18/min
  • SpO2 98% on room air
  • T 38.1ยฐC

Abdominal examination reveals generalised tenderness without guarding. Her PD catheter exit site appears clean.

He suggests this is โ€œalmost certainly PD peritonitisโ€ and plans to give empiric antibiotics and discharge her home.

1. Describe (2) key investigations that you would perform, including what result would support a diagnosis of PD-associated peritonitis. 4 marks

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2. List (2) specific treatment modalities for the most likely diagnosis, including appropriate treatment.List (2) specific treatment modalities for the most likely diagnosis, including appropriate treatment. 2 marks

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You would like to discharge this lady for treatment at home.

3. List (2) possible contraindications to this plan. 2 marks

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