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A 10-year-old boy with known Haemophilia A presents to the emergency department with an atraumatic painful knee. He is systemically well. His X-ray shows no fracture. His weight is 30kg and his vitals are normal.

1. What is Haemophilia A? 1 mark

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2. Complete the table with the concentration of clotting factors for each level of severity. 3 marks

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3. What is the likely diagnosis? 1 mark

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4. List (2) supportive management steps. 2 marks

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5. State the specific management, including dose and targets. 3 marks

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6. How would this dose be altered in the setting of an intracranial haemorrhage and why? 2 marks

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