MedBugs: SAQ #270

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Case: Jaundice

A 47-year-old male presents to your ED complaining of a change in his skin colour. He has no known past medical history and no relevant family history of note. He is clinically stable. Hb 65 WCC 8 PLT 230 AST 18 ALT 15 ALP 106 GGT 25 Bili 60

1. Give two possible causes for conjugated and unconjugated hyperbilirubinaemia. 4 marks

His results are: Conjugated bili 5 Unconjugated bili 55 On further questioning, you discover that the patient was recently commenced on an antimalarial medication ahead of his upcoming trip to Vanuatu.

2. What is the most likely diagnosis? 1 mark

3. List three other drugs that can cause this scenario. 3 marks

4. List and justify four further blood tests you would order. 4 marks

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Case: Jaundice

1. Give two possible causes for conjugated and unconjugated hyperbilirubinaemia. 4 marks

2. What is the most likely diagnosis? 1 mark

3. List three other drugs that can cause this scenario. 3 marks

4. List and justify four further blood tests you would order. 4 marks

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